Sexually transmitted infections (STIs), even when asymptomatic, alter the vaginal immune environment in ways that may increase susceptibility to other infections, such as HIV. Identifying and treating asymptomatic STIs represents an opportunity to mitigate their impact as drivers of the HIV epidemic. The authors state that it may be feasible to detect asymptomatic STIs in the clinical setting by using a point-of-care screening test that measures vaginal proteins that are altered during inflammation.
Inflammatory cytokine biomarkers of asymptomatic sexually transmitted infections and vaginal dysbiosis: A multicenter validation study
Written By
Masson L, Barnabas S, Deese J, Lennard K, Dabee S, Gamieldien H, Jaumdally SZ, Williamson AL, Little F, Van Damme L, Ahmed K, Crucitti T, Abdellati S, Bekker LG, Gray G, Dietrich J, Jaspan H, Passmore JA