Comprehensive profiling of HIV antibody evolution

Written By
Eshleman SH, Laeyendecker O, Kammers K, Chen A, Sivay MV, Kottapalli S, Sie BM, Yuan T, Monaco DR, Mohan D, Wansley D, Kula T, Morrison C, Elledge SJ, Brookmeyer R, Ruczinski I, Larman HB

This study evaluates HIV antibody responses and their evolution during the course of HIV infection. The data are used to design a prototype four-peptide ‘‘serosignature’’ to predict duration of HIV infection and can be used to identify recent HIV infections for the purpose of developing prevention interventions.

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