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Maximizing Options to Advance Informed Choice for HIV Prevention (MOSAIC)

U.S. Agency for International Development (USAID), U.S. President’s Emergency Plan for AIDS Relief (PEPFAR)
2021 - 2026

Maximizing Options to Advance Informed Choice for HIV Prevention (MOSAIC) is a five-year (2021-2026) global project funded by the U.S. President’s Emergency Plan for AIDS Relief (PEPFAR) through the U.S. Agency for International Development (USAID) to help adolescent girls and young women and other women* prevent HIV by accelerating introduction and scale-up of new and emerging biomedical prevention products.

MOSAIC will work across multiple countries to implement user-centered research and research translation efforts to identify, understand and remove barriers to new product introduction, access and use; coordinate and provide technical assistance to global, national and subnational stakeholders to expedite product launch and scale-up; and strengthen the capacity of a wide range of local partners to perform essential functions that support the introduction of HIV prevention products.

The MOSAIC consortium is led by FHI 360 along with core partners Wits Reproductive Health and HIV Institute (Wits RHI), Pangaea Zimbabwe AIDS Trust (PZAT), LVCT Health, Jhpiego and AVAC. Local partner leadership and engagement, particularly in sub-Saharan Africa, is intrinsic to the project's approach to expediting women's access to new HIV prevention products. The work will also be supported by technical partners from Afton Bloom, Avenir Health, Columbia University, Mann Global Health, RTI International, the University of Pittsburgh and the University of Washington.

Working closely with product developers, MOSAIC will advance access to and uptake within a multiproduct market that includes options such as oral pre-exposure prophylaxis (oral PrEP), the dapivirine ring (also called PrEP ring) and injectable long-acting cabotegravir (CAB PrEP). Proposed countries for the consortium’s work are Kenya, South Africa, Zambia, Zimbabwe, Eswatini, Lesotho, Uganda, Namibia, and Nigeria.

MOSAIC resources

*MOSAIC end users include cisgender women, transgender women, and nonbinary people and transgender men assigned female at birth; in addition, specific underrepresented groups within these end user populations include very young adolescents, sex workers, pregnant and breastfeeding individuals, those engaged in transactional sex, and individuals who use drugs.

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