This article suggests that the suppressive effects of hormonal contraceptives on vaginal immunity are modified by the presence of genital tract infections. Therefore, studies assessing the effects of hormonal contraception on HIV susceptibility and vaginal immunity may lead to different results in populations with differing levels and types of genital tract infections.
The contribution of cervicovaginal infections to the immunomodulatory effects of hormonal contraception
Written By
Fichorova RN, Chen PL, Morrison CS, Doncel GF, Mendonca K, Kwok C, Chipato T, Salata R, Mauck C.