As oral pre-exposure prophylaxis becomes more widely available, understanding the interaction of Truvada with other commonly used pharmaceuticals will become more important. In particular, reproductive-aged women at high risk of HIV are in need of highly effective methods both to protect themselves against HIV and to prevent pregnancy. This paper provides early data on the effect of Truvada on levonogestrel levels among women using Truvada for HIV prevention and Sino-implant (II) for contraception.
Sino-implant (II)® continuation and effect of concomitant tenofovir disoproxil fumarate-emtricitabine use on plasma levonorgestrel concentrations among women in Bondo, Kenya
Written By
Todd CS, Deese J, Wang M, Hubacher D, Steiner MJ, Otunga S, Van Damme L, Fem-PrEP study group.