The sensitivity and specificity of the Kalon and HerpeSelect IgG serological assays for HSV-2 diagnosis have been found to vary when using specimens from sub-Saharan Africa. The performance of both assays was compared and researchers determined that the sensitivity of the Kalon assay could be improved by lowering the index cut-off optical density value while maintaining high specificity.
Prevalence and incidence estimation of HSV-2 by two IgG ELISA methods among South African women at high risk of HIV
Written By
de Baetselier I, Menten J, Cuylaerts V, Ahmed K, Deese J, Van Damme L, Crucitti T.
