The vaginal and oral interventions to control the epidemic (VOICE) adherence strengthening program (VASP) revealed challenges to mid-study changes in the adherence support approach in a large multisite clinical trial. The research recommended that future adherence support packages: 1) use an integrated, multidisciplinary approach from study start; 2) use multiple modalities for participant engagement to best fit the local culture; and 3) document the fidelity of implementation so the potential impact of adherence support interventions can be assessed.
Perceptions and experiences with the VOICE adherence strengthening program (VASP) in the MTN-003 trial
Written By
van der Straten A, Mayo A, Brown ER, Amico KR, Cheng H, Laborde N, Marrazzo J, Torjesen K.
