Pre-exposure prophylaxis (PrEP) rollout can be hampered by concerns about expense and cost-effectiveness. This paper looked to determine for which populations and patterns of sexual behavior non-daily oral PrEP would substantially reduce the overall costs of PrEP delivery programs, compared with daily regimens, if each regimen was used exactly as prescribed. Nondaily oral PrEP could lower costs substantially, compared with daily PrEP, particularly in high-income countries. Adherence and efficacy data are needed to determine cost-effectiveness.
In what circumstances could nondaily preexposure prophylaxis for HIV substantially reduce program costs?
Written By
Mitchell KM, Dimitrov D, Hughes JP, Xia F, Donnell D, Amico KR, Bokoch K, Chitwarakorn A, Bekker LG, Holtz TH, Mannheimer S, Grant RM, Boily MC
