This study describes and assesses the association between symptomatic malaria and subsequent sub-clinical levels of parasites in the blood (parasitaemia). The authors found that treatment of Plasmodium vivax malaria with artemisinin-based combination therapy without primaquine often resulted in recurrent episodes. This data could be an important component of elimination strategies. Therefore, treatment with the aim of interrupting transmission should target the entire community.
History of malaria treatment as a predictor of subsequent subclinical parasitaemia: A cross-sectional survey and malaria case records from three villages in Pailin, western Cambodia
Written By
Peto TJ, Kloprogge SE, Tripura R, Nguon C, Sanann N, Yok S, Heng C, Promnarate C, Chalk J, Song N, Lee SJ, Lubell Y, Dhorda M, Imwong M, White NJ, von Seidlein L, Dondorp A