The study found a high prevalence of pretreatment HIV drug resistance, predominantly nonnucleoside reverse transcriptase inhibitor-based regimen (NNRTI) associated, among HIV-infected children (less than 18 months) in Nigeria. The findings support using a non-NNRTI regimen in children less than 3 years of age as a preferred first-line antiretroviral treatment regimen, as recommended by the World Health Organization. Child-friendly, fixed-dose, combination co-formulated drugs need to be widely available in the country.
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