Daily and non-daily pre-exposure prophylaxis in African women (HPTN 067/ADAPT Cape Town Trial): A randomised, open-label, Phase 2 trial

Written By
Bekker LG, Roux S, Sebastien E, Yola N, Amico KR, Hughes JP, Marzinke MA, Hendrix CW, Anderson PL, Elharrar V, Stirratt M, Rooney JF, Piwowar-Manning E, Eshleman SH, McKinstry L, Li M, Dye BJ, Grant RM, HPTN 067 (ADAPT) study team

The HIV Prevention Trails Network (HPTN) 067 trial, is a Phase 2, randomized, open-label oral pre-exposure prophylaxis (PrEP) behavioral study to evaluate the feasibility of non-daily regimens in adult women. The majority of women in this study took oral PrEP when made available in an open label study. Daily dosing resulted in better coverage during sex events, reported adherence and higher drug levels.

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