Cervicovaginal HIV shedding is associated with increased female-to-male and mother-to-child transmission. The authors identified a specific immune mediator profile that is associated with the risk of cervical HIV shedding. This information could be used to develop antimicrobial agents or identify women at high risk of onward HIV transmission.
Biomarkers of cervical inflammation and immunity associated with cervical shedding of HIV-1
Written By
Mauck C, Chen PL, Morrison CS, Fichorova RN, Kwok C, Chipato T, Salata RA, Doncel GF