Higher HIV genetic diversity may be associated with virologic outcomes in HIV-infected adults. In this study, the authors indicate that using a high-resolution melting assay to analyze the diversity can be used to show that HIV diversity can impact clinical outcomes and that it might be a valuable tool for future studies of people with HIV infection.
Association of HIV diversity and virologic outcomes in early antiretroviral treatment: HPTN 052
Written By
Palumbo PJ, Wilson EA, Piwowar-Manning E, McCauley M, Gamble T, Kumwenda N, Makhema J, Kumarasamy N, Chariyalertsak S, Hakim JG, Hosseinipour MC, Melo MG, Godbole SV, Pilotto JH, Grinsztejn B, Panchia R, Chen YQ, Cohen MS, Eshleman SH, Fogel JM