This report presents the final results of HIV Prevention Trials Network (HPTN) 052. The results demonstrate that antiretroviral therapy (ART) for HIV infection provides durable and reliable protection against sexual transmission of HIV from infected men and women to their HIV-uninfected sexual partners. This finding has galvanized a worldwide commitment to universal “treatment as prevention” for combating the HIV epidemic, with ART recommended for all people with HIV, regardless of CD4 cell count.
Antiretroviral therapy for the prevention of HIV-1 transmission
Written By
Cohen MS, Chen YQ, McCauley M, Gamble T, Hosseinipour MC, Kumarasamy N, Hakim JG, Kumwenda J, Grinsztejn B, Pilotto JH, Godbole SV, Chariyalertsak S, Santos BR, Mayer KH, Hoffman IF, Eshleman SH, Piwowar-Manning E, Cottle L, Zhang XC, Makhema J, Mills LA, Panchia R, Faesen S, Eron J, Gallant J, Havlir D, Swindells S, Elharrar V, Burns D, Taha TE, Nielsen-Saines K, Celentano DD, Essex M, Hudelson SE, Redd AD, Fleming TR, HPTN 052 study team