People who inject drugs have a high incidence of HIV, little access to antiretroviral therapy (ART) or medication-assisted treatment (MAT), and a high mortality rate. The authors assessed the feasibility of a future controlled trial based on the incidence of HIV, enrollment, retention and uptake of the intervention, and the efficacy of an integrated and flexible intervention on ART use, viral suppression, and MAT use. This study concluded that a flexible, scalable intervention could increase ART and MAT use and reduce mortality among this population.
A scalable, integrated intervention to engage people who inject drugs in HIV care and medication-assisted treatment (HPTN 074): A randomized, controlled phase 3 feasibility and efficacy study
Written By
Miller WC, Hoffman IF, Hanscom BS, Ha TV, Dumchev K, Djoerban Z, Rose SM, Latkin CA, Metzger DS, Lancaster KE, Go VF, Dvoriak S, Mollan KR, Reifeis SA, Piwowar-Manning EM, Richardson P, Hudgens MG, Hamilton EL, Sugarman J, Eshleman SH, Susami H, Chu VA, Djauzi S, Kiriazova T, Bui DD, Strathdee SA, Burns DN
