The transport corridors of east, central and southern Africa that link countries with their neighbors are also major transmission routes for HIV. Truck drivers, traders, businesspeople, staff in bars and lodgings, border and customs officers, and others who live or work along these corridors are at elevated risk of HIV infection. High unemployment, multiple concurrent sexual partnerships, heavy alcohol consumption, widespread gender-based violence and poor access to quality health services — including HIV prevention, care and treatment services — all fuel the spread of HIV.

FHI 360’s Regional Outreach Addressing AIDS through Development Strategies (ROADS) project has linked communities along these corridors with critical HIV/AIDS and other health services by collaborating closely with national AIDS control programs; government ministries; district health management teams; health facilities; and local, national and international companies. The project helps individuals and communities reduce their vulnerability to HIV by expanding economic opportunities and improving food security. The project's LifeWorks component provides training and technical assistance in group savings and loan, livestock management (chickens, rabbits and goats), urban and organic gardening and microenterprise development. The ROADS project also provides care and support for orphans and other at-risk children, and it works to protect women and girls from sexual exploitation and abuse. ROADS II is currently active in the following countries: Burundi, Democratic Republic of the Congo, Djibouti, Kenya, Mozambique, Rwanda, Tanzania, Uganda and Zambia.