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HealthPublished researchMonitoring and evaluationHIV and AIDS

16 Results Found

  • Published research

    Certification of lay providers to deliver key population‐led HIV services in Thailand's National Healthcare System: Lessons learned

  • Published research

    The case for prevention–Primary HIV prevention in the era of universal test and treat: A mathematical modeling study

  • Published research

    Client-centered adherence counseling with adherence measurement feedback to support use of the dapivirine ring in MTN-025 (The HOPE Study)

  • Published research

    Development and initial validation of a simple tool to screen for partner support or opposition to HIV prevention product use

  • Published research

    Adolescents living with HIV in the Copperbelt Province of Zambia: Their reproductive health needs and experiences

    The authors conducted interviews with adolescents living with HIV in Zambia to assess the extent to which their reproductive health needs are being met. The results state that these adolescents need comprehensive sexual and reproductive health services. This includes information about contraceptive methods, healthy pregnancy and prevention of mother-to-child transmission, skills on HIV disclosure and condom negotiation to prevent horizontal transmission, and screening for sexual violence for both males and females.
  • Published research

    Brief participant-centered convergence interviews integrate self-reports, product returns, and pharmacokinetic results to improve adherence measurement in MTN-017

    Studies of HIV prevention products face challenges with adherence and adherence reporting. This paper presents the convergence interviews that were developed and implemented during the Microbicide Trials Network (MTN) 017 study. The authors demonstrated that brief convergence interviews and pharmacokinetic data convergence interviews were feasible in adherence counseling sessions and, in general, participants would clarify with the counselors any discrepancies between adherence measures.
  • Published research

    Prevalence of sexually transmitted infections and bacterial vaginosis among women in sub-Saharan Africa: An individual participant data meta-analysis of 18 HIV prevention studies

    Estimates of sexually transmitted infection (STI) prevalence are essential for efforts to prevent and control STIs. This study used a two-stage meta-analysis to estimate the prevalence of chlamydia, gonorrhea, trichomoniasis, syphilis, herpes simplex virus type 2 (HSV-2) and bacterial vaginosis (BV) among women in sub-Saharan Africa. These findings highlight important features of STI and BV epidemiology. The authors state this methodology can be used where routine STI surveillance is limited and offers a new approach to obtaining critical information on STI and BV prevalence in low- and middle-income countries.
  • Published research

    It’s all in the timing: Acceptability of a financial incentive intervention for linkage to HIV care in the HPTN 065 (TLC-Plus) study

    This qualitative research was conducted with participants and implementers of a financial incentive intervention to link newly diagnosed HIV-infected patients into HIV care. The authors state that patients and providers found the financial incentives to be favorable overall, but implementation challenges suggest that future similar interventions for linkage-to-care should consider optimal timing and presentation of financial incentives, how to overcome negative attitudes toward incentives and how to integrate incentives into existing linkage programs.
  • Published research

    A review on tuberculosis in human immunodeficiency virus infection

    Tuberculosis (TB) is the most common opportunistic infection and the leading cause of death among people living with HIV and AIDS. The paper reviews the activating effects of TB in HIV infection. The authors found that both the immunologic and virologic evidence show that patients’ immune responses to TB enhance HIV replication and might also enhance progression of HIV infection.
  • Published research

    Higher sequence diversity in the vaginal tract than in blood at early HIV-1 infection

    This analysis of early mucosal infections in women revealed high HIV-1 viral diversity in the vaginal tract but few transmitted clones in the blood. This provides novel in vivo evidence for a mucosal sieve effect, leading to the establishment of a homogenous systemic infection. The data will have significant implications in rational vaccine design.