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ResearchHealth researchHIV preventionHIV and AIDS

9 Results Found

  • Published research

    Brief report: Herpes simplex virus type-2 shedding and genital ulcers during early HIV in Zimbabwean women

  • Published research

    Risk factors for TB/HIV coinfection and consequences for patient outcomes: Evidence from 241 clinics in the Democratic Republic of Congo

  • Published research

    Disparities in HIV clinical stages progression of patients at outpatient clinics in Democratic Republic of Congo

  • Published research

    High prevalence of HIV drug resistance among newly diagnosed infants aged <18 months: Results from a nationwide surveillance in Nigeria

    The study found a high prevalence of pretreatment HIV drug resistance, predominantly nonnucleoside reverse transcriptase inhibitor-based regimen (NNRTI) associated, among HIV-infected children (less than 18 months) in Nigeria. The findings support using a non-NNRTI regimen in children less than 3 years of age as a preferred first-line antiretroviral treatment regimen, as recommended by the World Health Organization. Child-friendly, fixed-dose, combination co-formulated drugs need to be widely available in the country.
  • Published research

    Safety and tolerability of maraviroc-containing regimens to prevent HIV infection in women: A phase 2 randomized trial

    This study shows that, for U.S. women at risk of HIV infection, pre-exposure prophylaxis (PrEP) regimens containing maraviroc are safe and well-tolerated, compared with the standard regimen of tenofovir disoproxil fumarate/emtricitabine. The authors also found that no new infections occurred with the study regimen, compared with the standard regimen, but more research is needed to determine whether that outcome is because of the study drug and whether the enrolled population was lower risk than anticipated.
  • Published research

    Design of the HPTN 065 (TLC-Plus) study: A study to evaluate the feasibility of an enhanced test, linkto-care, plus treat approach for HIV prevention in the United States

    This article outlines the design of a multicomponent, community-based study evaluating the feasibility of the “test and treat” approach to HIV prevention in the United States. The authors found that the HIV Prevention Trails Network (HPTN) 065 study demonstrated the feasibility of implementing and evaluating a trial that includes several community sites and involves pragmatic approaches to study implementation and evaluation.
  • Tools

    Pathways to High Adherence: An Adherence Support Manual for Vaginal Ring Trials

    This manual provides research staff of HIV prevention clinical trials with strategies to support adherence to the use of antiretroviral-based vaginal rings and potentially other HIV prevention products.
  • Feature

    FHI 360 facilitates the next generation of public health researchers in Zambia

    Today, Zambia is faced with a complex set of challenges, including high rates of HIV, an overburdened national health system and a lack of researchers dedicated to resolving these issues.   
  • Past Project

    PrEP and Risk Compensation: Assessing Effect and Preparing for Rollout

    Since 2010, research has demonstrated the efficacy of pre-exposure prophylaxis (PrEP) in reducing HIV acquisition. The U.S. Food and Drug Administration has approved the use of Truvada for HIV prevention, and both the U.S. Centers for Disease...