Explore FHI 360

82 Results Found

  • Feature
    Markus Steiner and Kate Rademacher of FHI 360 discuss the long-term effort to increase global access to contraceptive implants at an affordable price.
  • Published research
    Effect of self-administration versus provider-administered injection of subcutaneous depot medroxyprogesterone acetate on continuation rates in Malawi: A randomised controlled trial
    The authors found that women who self-administered subcutaneous depot medroxyprogesterone acetate (DMPA-SC) led to a more than 50 percent increase in pregnancy protection through 12 months compared with provider-administered injection. The findings demonstrate that self-injection can address the stubborn problem of early contraceptive discontinuation and that community health workers can safely train women to self-inject. Malawi plans to introduce DMPA-SC self-injection based on these positive findings.
  • Published research
    Outcomes of compulsory detention compared to community-based voluntary methadone maintenance treatment in Vietnam
    This research finds conclusive evidence that methadone maintenance treatment (MMT) is more costeffective than center-based compulsory treatment (CCT) in reducing heroin use, blood-borne virus risk behaviors, drug-related illegal behaviors and monthly drug spending. The authors recommend that policymakers consider allocation of resources for MMT treatment a higher priority and scale down CCT models.
  • Published research
    Factors related to incomplete adherence to antiretroviral therapy among adolescents attending three HIV clinics in the Copperbelt, Zambia
    The authors assessed antiretroviral adherence among adolescents in Ndola, Zambia, using two measures: 48-hour treatment gap in prior three months and pharmacy medication possession ratio in prior six months. The findings support strengthening adolescents’ HIV management skills related to alcohol use, family engagement and the challenges adolescents face when transitioning to adulthood, especially when they are no longer in school.
  • Published research
    OMNIgene.SPUTUM suppresses contaminants while maintaining Mycobacterium tuberculosis viability and obviates cold-chain transport
    According to current World Health Organization recommendations, tuberculosis samples should be transported under cold-chain conditions (2-8°C) and processed within 24-48 hours, which is an unrealistic situation in most of the health facilities in Mozambique. This paper evaluates OMNIgene.SPUTUM, a new tool that maintains the quality of samples without cold-chain transport.
  • Feature
    In Nigeria, the Akwa Ibom AIDS Indicator Survey (AKAIS) generated more accurate data than previously available. The data will be used to improve Akwa Ibom State’s response to HIV.
  • Published research
    QUENTIN: Reconstruction of disease transmissions from viral quasispecies genomic data
    Genomic analysis has become one of the major tools for disease outbreak investigations. This paper proposes a Quasispecies Evolution, Network-based Transmission Inference (QUENTIN) framework for conducting genomic analyses of outbreaks of highly mutable viruses associated with chronic infections, such as HIV and hepatitis C virus. The QUENTIN framework uses relevant properties of social networks to address previously identified shortcomings of existing computational frameworks for inference of transmission history from viral genomic data.
  • Published research
    A measurement error model approach to survey data integration: Combining information from two surveys
    Combining information from two surveys is a challenge in survey sampling, particularly when there are overlapping geographies. In such cases, dual frame estimation methods are employed to derive overall estimates while avoiding double contributions coming from the overlap area. In this paper, measurement error models were layered onto the dual frame approach, to appropriately account for potential measurement errors. The approach can be generalized to combine more than two sources of information.
  • Published research
    Comparing focus groups and individual interviews: Findings from a randomized study
    Researchers often question using focus groups or individual interviews for their studies. The findings in this article are based on a randomized study in which data from focus groups and individual interviews were compared. The authors found that sensitive and personal disclosures were more likely in a focus group and some sensitive themes only occurred in a focus group. The authors suggest these findings can help researchers align qualitative data collections methods with study objectives.
  • News
    FHI 360 is providing monitoring services for a trial to evaluate a DNA vaccine for the Zika virus, which could protect healthy adults and adolescents.