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15 Results Found

  • Feature
    In Nigeria, the Akwa Ibom AIDS Indicator Survey (AKAIS) generated more accurate data than previously available. The data will be used to improve Akwa Ibom State’s response to HIV.
  • Published research
    A measurement error model approach to survey data integration: Combining information from two surveys
    Combining information from two surveys is a challenge in survey sampling, particularly when there are overlapping geographies. In such cases, dual frame estimation methods are employed to derive overall estimates while avoiding double contributions coming from the overlap area. In this paper, measurement error models were layered onto the dual frame approach, to appropriately account for potential measurement errors. The approach can be generalized to combine more than two sources of information.
  • Published research
    Comparing focus groups and individual interviews: Findings from a randomized study
    Researchers often question using focus groups or individual interviews for their studies. The findings in this article are based on a randomized study in which data from focus groups and individual interviews were compared. The authors found that sensitive and personal disclosures were more likely in a focus group and some sensitive themes only occurred in a focus group. The authors suggest these findings can help researchers align qualitative data collections methods with study objectives.
  • Published research
    Safety and tolerability of maraviroc-containing regimens to prevent HIV infection in women: A phase 2 randomized trial
    This study shows that, for U.S. women at risk of HIV infection, pre-exposure prophylaxis (PrEP) regimens containing maraviroc are safe and well-tolerated, compared with the standard regimen of tenofovir disoproxil fumarate/emtricitabine. The authors also found that no new infections occurred with the study regimen, compared with the standard regimen, but more research is needed to determine whether that outcome is because of the study drug and whether the enrolled population was lower risk than anticipated.
  • Published research
    HIV prevalence and factors associated with HIV infection among transgender women in Cambodia: Results from a national Integrated Biological and Behavioral Survey
    This study was the second national biological and behavioral survey among transgender women in Cambodia. The authors found that HIV prevalence among transgender women remains persistently high. To achieve the goal of eliminating HIV, they suggest that effective combination prevention strategies addressing the risk factors among transgender women be strengthened.
  • Published research
    Effect of low-to-moderate-dose corticosteroids on mortality of hospitalized adolescents and adults with influenza A(H1N1)pdm09 viral pneumonia
    The authors analyzed the effect of corticosteroids to reduce mortality from pneumonia caused by a specific strain of influenza A called (H1N1)pdm09. Using observational data of hospitalized adolescent and adult patients with this type of pneumonia, the findings suggest that low-to-moderate-dose corticosteroids might reduce the mortality of patients with severe pneumonia that causes low blood oxygen levels. However, there was no indication that patients with less severe disease benefited from corticosteroid therapy.
  • Published research
    Evidence-based strategies for shortening informed consent forms in clinical research
    Long informed consent forms can negatively affect potential participants’ understanding of clinical research. The authors present three strategies for reducing form length that were developed by consensus among six groups of key stakeholders. Implementing these strategies will facilitate adoption of the proposed changes to U.S. regulations on form length, to make the consent process more useful for participants. 
  • News
    The U.S. President's Emergency Plan for AIDS Relief (PEPFAR) named FHI 360 a winner of the DREAMS Innovation Challenge for the Communities Investing in Education for Child Health and Safety project.
  • Project
    The Africa DREAMS: Malawi Communities Investing in Education for Child Health and Safety (CIECHS) project focuses on gender and education as critical ways to reduce the incidence of HIV. CIECHS is funded by the DREAMS Innovation Challenge.
  • Published research
    Verification of chemistry reference ranges using a simple method in sub-Saharan Africa
    Chemistry reference ranges are often unavailable for local populations participating in international clinical trials. This paper identifies a simple approach to defining normal hepatic and biochemistry ranges among clinical trial participants. Embedding the process early in the screening phase of a clinical trial is cost-effective and may reveal population differences that are important in classifying toxicities that occur during the trial.