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6 Results Found

  • Published research

    Re-envisioning Kangaroo Mother Care implementation through a socioecological model: Lessons from Malawi

  • Published research

    Sauti ya Vijana (SYV; The Voice of Youth): Longitudinal outcomes of an individually randomized group treatment pilot trial for young people living with HIV in Tanzania

  • Published research

    Tenofovir diphosphate concentrations in dried blood spots from pregnant and postpartum adolescent and young women receiving daily observed pre-exposure prophylaxis in Sub-Saharan Africa

  • Published research

    Pharmacokinetics of dapivirine transfer into blood plasma, breast milk, and cervicovaginal fluid of lactating women using dapivirine vaginal ring

    This study assessed the pharmacokinetics, safety, tolerability and adherence of the dapivirine vaginal ring used for 14 consecutive days by lactating women who were not breastfeeding. The research showed low concentrations of dapivirine in breast milk, indicating that daily infant exposure would also be low. Given this favorable safety profile, additional research is in development to assess the safety and drug detection of the dapivirine ring in breastfeeding mother-infant pairs in regions with higher incidence of sexually transmitted HIV infection.
  • Published research

    Outcomes of compulsory detention compared to community-based voluntary methadone maintenance treatment in Vietnam

    This research finds conclusive evidence that methadone maintenance treatment (MMT) is more costeffective than center-based compulsory treatment (CCT) in reducing heroin use, blood-borne virus risk behaviors, drug-related illegal behaviors and monthly drug spending. The authors recommend that policymakers consider allocation of resources for MMT treatment a higher priority and scale down CCT models.
  • Published research

    Safety and tolerability of maraviroc-containing regimens to prevent HIV infection in women: A phase 2 randomized trial

    This study shows that, for U.S. women at risk of HIV infection, pre-exposure prophylaxis (PrEP) regimens containing maraviroc are safe and well-tolerated, compared with the standard regimen of tenofovir disoproxil fumarate/emtricitabine. The authors also found that no new infections occurred with the study regimen, compared with the standard regimen, but more research is needed to determine whether that outcome is because of the study drug and whether the enrolled population was lower risk than anticipated.