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3 Results Found

  • Published research

    Effect of self-administration versus provider-administered injection of subcutaneous depot medroxyprogesterone acetate on continuation rates in Malawi: A randomised controlled trial

    The authors found that women who self-administered subcutaneous depot medroxyprogesterone acetate (DMPA-SC) led to a more than 50 percent increase in pregnancy protection through 12 months compared with provider-administered injection. The findings demonstrate that self-injection can address the stubborn problem of early contraceptive discontinuation and that community health workers can safely train women to self-inject. Malawi plans to introduce DMPA-SC self-injection based on these positive findings.
  • Published research

    Outcomes of compulsory detention compared to community-based voluntary methadone maintenance treatment in Vietnam

    This research finds conclusive evidence that methadone maintenance treatment (MMT) is more costeffective than center-based compulsory treatment (CCT) in reducing heroin use, blood-borne virus risk behaviors, drug-related illegal behaviors and monthly drug spending. The authors recommend that policymakers consider allocation of resources for MMT treatment a higher priority and scale down CCT models.
  • Published research

    Safety and tolerability of maraviroc-containing regimens to prevent HIV infection in women: A phase 2 randomized trial

    This study shows that, for U.S. women at risk of HIV infection, pre-exposure prophylaxis (PrEP) regimens containing maraviroc are safe and well-tolerated, compared with the standard regimen of tenofovir disoproxil fumarate/emtricitabine. The authors also found that no new infections occurred with the study regimen, compared with the standard regimen, but more research is needed to determine whether that outcome is because of the study drug and whether the enrolled population was lower risk than anticipated.