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Health researchHealth and access to careResearch servicesHIV and AIDS

4 Results Found

  • Published research

    Sauti ya Vijana (SYV; The Voice of Youth): Longitudinal outcomes of an individually randomized group treatment pilot trial for young people living with HIV in Tanzania

  • Published research

    Pharmacokinetics of dapivirine transfer into blood plasma, breast milk, and cervicovaginal fluid of lactating women using dapivirine vaginal ring

    This study assessed the pharmacokinetics, safety, tolerability and adherence of the dapivirine vaginal ring used for 14 consecutive days by lactating women who were not breastfeeding. The research showed low concentrations of dapivirine in breast milk, indicating that daily infant exposure would also be low. Given this favorable safety profile, additional research is in development to assess the safety and drug detection of the dapivirine ring in breastfeeding mother-infant pairs in regions with higher incidence of sexually transmitted HIV infection.
  • Published research

    Safety and tolerability of maraviroc-containing regimens to prevent HIV infection in women: A phase 2 randomized trial

    This study shows that, for U.S. women at risk of HIV infection, pre-exposure prophylaxis (PrEP) regimens containing maraviroc are safe and well-tolerated, compared with the standard regimen of tenofovir disoproxil fumarate/emtricitabine. The authors also found that no new infections occurred with the study regimen, compared with the standard regimen, but more research is needed to determine whether that outcome is because of the study drug and whether the enrolled population was lower risk than anticipated.
  • Past Project

    Zimbabwe HIV Care and Treatment (ZHCT)

    The ZHCT project supports community-level HIV care and treatment services as well as strengthens the linkages between health facilities providing HIV services.