Nirupama Sista, PhDDirector, HPTN Leadership and Operations Center
Areas of expertise
- HIV prevention
- Drug development
- Antiretroviral drugs
- Clinical research
Projects & Resources
FHI 360 serves as the leadership and operations center for the HIV Prevention Trials Network (HPTN), a worldwide, collaborative, clinical trials network that develops and tests the safety and efficacy of primarily nonvaccine interventions to prevent the transmission of HIV.
Published Research/** * @file * Unformatted override for published research. * Using the same markup as "project" because it's the same */ ?>
ARV-based HIV prevention for women – where we are in 2014
Mastro TD, Sista N, Abdool-Karim Q
Journal of the International AIDS Society. 2014; 17 (suppl 2): 19154
Women continue to be at special risk for HIV acquisition due to a complex mix of biological, behavioral, structural, cultural and social factors, with unacceptable rates of new infection. Scientific advances over the past decade have highlighted the use of antiretroviral (ARV) drugs as pre-exposure prophylaxis (PrEP) to prevent HIV acquisition (sexually, parenterally and vertically) and ARV treatment (ART) for HIV-positive patients to prevent onward transmission (treatment as prevention, or TasP). This paper reviews the evidence base for PrEP and TasP and describes new products in development and the need to translate research findings into programs with impact at the population level.